Welcome to Guidechem,Sign In or Join free now ?

AZD 7762;AZD7762;AZD-7762CAS: 860352-01-8

  • FOB Price:
  • Port:
  • Minimum Order Quantity:
    5 Gram
  • Supply Ability:
    5  Kilogram/Month
  • Payment Terms:
    Western Union,
Quick Details
Synonyms: 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide Classification: Pharmaceuticals and Biochemicals
EINECS: Molecular Formula: C17H19FN4O2S
Melting Point: Boiling Point: 547.6 °C at 760 mmHg
Stability: Water Solubility:
Refractive index: Flash Point: 285 °C
Purity: Appearance:
HazardClass: Brand Name:
Packaging & Delivery
Packaging Detail:
Delivery Detail:
Detailed Description

AZD-7762 is a novel checkpoint kinase inhibitor with an IC50 of 5 and <10 nM for CHK1 and CHK2, respectively. AZD-7762 significantly prolonged the median time required for tumor volume doubling in response to gemcitabine and radiation. Together, findings suggest that G(2) checkpoint abrogation and homologous recombination repair inhibition both contribute to sensitization by Chk1 inhibition. Furthermore, they support the clinical use of AZD-7762 in combination with gemcitabine and radiation for patients with locally advanced pancreatic cancer.

 


Send your message to this supplier

Notice:*are required
*Email: Enter email
To: Dr.Gao(ChemScene,LLC)
*Subject:
*Message:

-Enter between 20 to 2,000 characters. English only. Word count: 0 character(s).

-We suggest you include in your inquiry a brief introduction to your company as well as your product requirements.

Levels:Free member
Type:Manufacturer
Last Login:2017-06-21

Dr. Gao

Tel:732-484-9848
Fax:888-484-5008
Address:11 Deer Park Drive, Suite 102D, Monmouth Junction