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MK-4305;Suvorexant; MK 4305CAS: 1030377-33-3

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Quick Details
Synonyms: Classification: Pharmaceuticals and Biochemicals
EINECS: Molecular Formula: C23H23ClN6O2
Melting Point: Boiling Point: 669.803 °C at 760 mmHg
Stability: Water Solubility:
Refractive index: Flash Point: 358.884 °C
Purity: >98% Appearance:
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Detailed Description

Suvorexant (MK-4305) is a potent, selective, and orally bioavailable antagonist of OX1R and OX2R currently under clinical investigation as a novel therapy for insomnia.Orexins/hypocretins are key neuropeptides responsible for regulating central arousal and reward circuits. Two receptors respond to orexin signaling, orexin 1 receptor (OX1R) and orexin 2 receptor (OX2R) with partially overlapping nervous system distributions. Genetic studies suggest orexin receptor antagonists could be therapeutic......


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Last Login:2017-06-21

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