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Odanacatib;MK-0822;MK 0822;MK0822;Pentanamide,N-(1-cyanocyclopropyl)-4-fluoro-4-methyl-2-[[(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]ethyl]amino]-,(2S)-CAS: 603139-19-1

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Quick Details
Synonyms: Odanacatib; Classification: Pharmaceuticals and Biochemicals
EINECS: Molecular Formula: C25H27F4N3O3S
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Detailed Description

Odanacatib (MK 0822) is an inhibitor of cathepsin K with potential anti-osteoporotic activity. Odanacatib selectively binds to and inhibits the activity of cathepsin K (IC50=0.2nM), which may result in a reduction in bone resorption, improvement of bone mineral density, and a reversal in osteoporotic changes. Odanacatib is currently in clinical development for the treatment of postmenopausal osteoporosis

 


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